Trichloroisocyanuric acid (TCCA)-TMSOTf: an efficient activator system for glycosylation reactions based on thioglycosides

Trichloroisocyanuric acid (TCCA), a readily available, inexpensive and shelf-stable reagent, in combination with a catalytic amount of TMSOTf, has been used for the first time for efficient glycosylation reactions based on thioglycoside donors with SEt, SPh and S-pTol leaving groups at the anomeric centres.