Journal
ORAL AND MAXILLOFACIAL SURGERY CLINICS OF NORTH AMERICA
Volume 26, Issue 2, Pages 123-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.coms.2014.01.001
Keywords
Epidemiologic trends; Head and neck cancer; Diagnosis; Squamous cell carcinomas
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Funding
- Cancer Prevention Research Institute of Texas (CPRIT) [RP101382, RP100932]
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Head and neck squamous cell carcinoma is the sixth most common cancer worldwide predominately associated with tobacco use. Changing cause and increased incidence in oropharyngeal carcinomas is associated with high-risk types of human papilloma virus and has an improved survival. Optical devices may augment visual oral examination; however, their lack of specificity still warrants tissue evaluation/biopsy. Histologic factors of oral carcinomas are critical for patient management and prognostic determination. Clinical biomarkers are still needed to improve early detection, predict malignant transformation, and optimize therapies.
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