Journal
NUTRIENTS
Volume 2, Issue 2, Pages 128-170Publisher
MDPI
DOI: 10.3390/nu2020128
Keywords
omega-3 polyunsaturated fatty acids; mental health; attention deficit hyperactivity disorder; autism; aggression; depression; dementia
Categories
Funding
- Australian Research Council (ARC) [LP0776922]
- South Australian Health Department
- Australian Research Council [LP0776922] Funding Source: Australian Research Council
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Around one in four people suffer from mental illness at some stage in their lifetime. There is increasing awareness of the importance of nutrition, particularly omega-3 polyunsaturated fatty acids (n-3 PUFA), for optimal brain development and function. Hence in recent decades, researchers have explored effects of n-3 PUFA on mental health problems over the lifespan, from developmental disorders in childhood, to depression, aggression, and schizophrenia in adulthood, and cognitive decline, dementia and Alzheimer's disease in late adulthood. This review provides an updated overview of the published and the registered clinical trials that investigate effects of n-3 PUFA supplementation on mental health and behavior, highlighting methodological differences and issues.
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