Journal
NEUROSCIENCE BULLETIN
Volume 28, Issue 5, Pages 641-648Publisher
SPRINGER
DOI: 10.1007/s12264-012-1272-0
Keywords
metabolomics; biomarkers; Alzheimer's disease
Categories
Funding
- National Basic Research Development Program of China [2010CB945200]
- National Natural Science Foundation of China [81171027]
- Shanghai Jiao Tong University Program for Morningstar Young Scholars
- Shanghai Key Discipline Program [S30202]
- Shanghai Natural Scientific Fund [09JC1416402, 09ZR1419100]
- Shanghai Key Project of Basic Science Research [09DZ1950400]
Ask authors/readers for more resources
Although the pathogenesis of Alzheimer's disease (AD) is still not fully understood, it is acknowledged that intervention should be made at the early stage. Therefore, identifying biomarkers for the clinical diagnosis is critical. Metabolomics, a novel omics, uses methods based on low-molecular-weight molecules, with high-throughput evaluation of a large number of metabolites that may lead to the identification of new disease-specific biomarkers and the elucidation of pathophysiological mechanisms. This review discusses metabolomics investigations of AD and potential future developments in this field.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available