Journal
NATURE CLINICAL PRACTICE RHEUMATOLOGY
Volume 4, Issue 11, Pages 590-596Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ncprheum0920
Keywords
dietary antioxidants; etiology; inflammatory arthritis; mechanisms; oxidative stress
Categories
Ask authors/readers for more resources
Rheumatoid arthritis is an autoimmune-mediated inflammatory disease of unknown etiology, and is characterized by joint pain and soft-tissue swelling. The role of dietary antioxidants in the prevention and amelioration of symptoms in inflammatory joint disease has been of interest for many years. Epidemiological studies provide evidence of a link between dietary antioxidant intake and the likelihood of developing inflammatory arthritis. Interventional studies of antioxidant Supplementation in established disease have been inconclusive overall; however, the quality Of Such studies has often been poor. The pathways by which antioxidant compounds might act are now better understood. Ill this Review, we explore not only some of the accepted mechanisms of antioxidant function but also Outline some concepts that could aid further investigation of the potential therapeutic role of dietary antioxidants in inflammatory arthritis.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available