Journal
NATURE CLINICAL PRACTICE CARDIOVASCULAR MEDICINE
Volume 5, Issue 10, Pages 621-635Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ncpcardio1322
Keywords
coronary disease; diabetes mellitus; prevention; risk factors; stroke
Categories
Funding
- NHLBI NIH HHS [T32 HL007208-31, T32 HL007208] Funding Source: Medline
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [T32HL007208] Funding Source: NIH RePORTER
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High-sensitivity assays that accurately measure levels of the inflammatory biomarker C-reactive protein have been proposed for use in assessments of risk for cardiovascular disease (CVD). A growing body of evidence supports recommendations for these tests in selected asymptornatic individuals deemed to be at intermediate risk of CVD according to traditional risk-factor assessments and who do not already warrant chronic treatment with aspirin and statin therapy. Data suggests that these high-sensitivity assays should be used in combination with measurements of LDL-cholesterol levels to assist risk stratification of selected patients for prevention of CVD.
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