Journal
NATURE CLINICAL PRACTICE CARDIOVASCULAR MEDICINE
Volume 5, Issue -, Pages S103-S111Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ncpcardio1242
Keywords
cardiovascular disease; molecular imaging; multimodality; nanoparticles; nanotechnology
Categories
Ask authors/readers for more resources
Targeted imaging and therapeutics is becoming a field of prime importance in the study and treatment of cardiovascular disease; it promises to enable early diagnosis, promote improved understanding of pathology, and offer a way to improve therapeutic efficacy. Agents, particularly for cardiovascular disease, have been reported to permit the in vivo imaging, by multiple modalities, of macrophages, vascular targets such as vascular cell adhesion molecule 1, and markers for angiogenesis such as alpha(V)beta(3) integrin. In this Article, we first discuss the general concept of multimodality nanoparticles and then focus in greater depth on their clinical application for molecular imaging and therapy. Lastly, several examples of cardiovascular applications are discussed, including combined imaging and therapy approaches.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available