Journal
STEM CELL REVIEWS AND REPORTS
Volume 12, Issue 2, Pages 202-213Publisher
SPRINGER
DOI: 10.1007/s12015-015-9641-5
Keywords
Extracellular matrix; Mechanotransduction; Heart; Stem cell therapy; Cardiac tissue engineering; Heart failure; Myocardial infarction; Tensegrity
Funding
- Turkish Academy of Sciences (TUBA, Ankara, Turkey)
Ask authors/readers for more resources
Cardiovascular diseases are the leading cause of death and a major cause of financial burden. Regenerative therapies for heart diseases bring the promise of alternative treatment modalities for myocardial infarction, ischemic heart disease, and congestive heart failure. Although, clinical trials attest to the safety of stem cell injection therapies, researchers need to overcome the underlying mechanisms that are limiting the success of future regenerative options. This article aims to review the basic scientific concepts in the field of mechanobiology and the effects of extracellular functions on stem cell fate.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available