Journal
MATERIALS
Volume 11, Issue 9, Pages -Publisher
MDPI
DOI: 10.3390/ma11091768
Keywords
lipid droplets; fluorescent probes; bioimaging
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Funding
- ERC [648528]
- ANR [ANR-16-CE11-0010]
- Agence Nationale de la Recherche (ANR) [ANR-16-CE11-0010] Funding Source: Agence Nationale de la Recherche (ANR)
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Lipid droplets (LDs) are organelles that serve as the storage of intracellular neutral lipids. LDs regulate many physiological processes. They recently attracted attention after extensive studies showed their involvement in metabolic disorders and diseases such as obesity, diabetes, and cancer. Therefore, it is of the highest importance to have reliable imaging tools. In this review, we focus on recent advances in the development of selective fluorescent probes for LDs. Their photophysical properties are described, and their advantages and drawbacks in fluorescence imaging are discussed. At last, we review the reported applications using these probes including two-photon excitation, in vivo and tissue imaging, as well as LDs tracking.
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