Journal
MATERIALS
Volume 5, Issue 11, Pages 2292-2305Publisher
MDPI
DOI: 10.3390/ma5112292
Keywords
liposome; droplet; cell-sized confinement; lipid membrane; DNA; compartmentalization; nanoparticle
Categories
Funding
- JSPS [23240044, 23740316]
- MEXT of Japan [24115505]
- Suntory Institute for Bioorganic Research
- Grants-in-Aid for Scientific Research [24115505, 23740316, 23240044] Funding Source: KAKEN
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Recent developments in studies concerning cell-sized vesicles, such as liposomes with a lipid bilayer and water-in-oil droplets covered by a lipid monolayer, aim to realize the real-world modeling of living cells. Compartmentalization with a membrane boundary is essential for the organization of living systems. Due to the relatively large surface/volume ratio in microconfinement, the membrane interface influences phenomena related to biological functions. In this article, we mainly focus on the following subjects: (i) conformational transition of biopolymers in a confined space; (ii) molecular association on the membrane surface; and (iii) remote control of cell-sized membrane morphology.
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