4.2 Article

Imaging of Endolymphatic and Perilymphatic Fluid after Intravenous Administration of Single-dose Gadodiamide

Journal

MAGNETIC RESONANCE IN MEDICAL SCIENCES
Volume 11, Issue 2, Pages 145-150

Publisher

JPN SOC MAGNETIC RESONANCE IN MEDICINE
DOI: 10.2463/mrms.11.145

Keywords

intravenous; magnetic resonance imaging; Meniere's disease; 3D imaging

Funding

  1. Grants-in-Aid for Scientific Research [24791288] Funding Source: KAKEN

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To visualize endolymph as bright signal after intravenous injection of single-dose gadodiamide, we shortened the inversion time of heavily T-2-weighted 3-dimensional (3D) fluid-attenuated inversion recovery (FLAIR) to 2050 ms. In 14 patients with suspected Meniere's disease, we observed high signal of vestibular endolymph in all ears, including 6 ears without vestibular endolymphatic hydrops. We observed high signal of cochlear endolymph in 17 ears with cochlear endolymphatic hydrops but not 11 ears without cochlear endolymphatic hydrops.

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