Journal
JALA
Volume 14, Issue 6, Pages 407-412Publisher
ELSEVIER INC
DOI: 10.1016/j.jala.2009.05.002
Keywords
microfluidics; electrochemical sensor; multiplexed assay; quantiative; molecular analysis; point of care; clinical diagnostics
Funding
- National Institute of Biomedical Imaging and Bioengineering [R01 EB00127]
- National Institute of Allergy and Infectious Diseases [U01 A1075565-01, U01 A1082457-01]
- National Institute of Dental and Craniofacial Research [U01 DE I 7790]
- Department of Veterans Affairs Merit Review [B4872R]
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Cartridge-based microfluidics is a promising technology for clinical diagnostics. By miniaturizing the fluid-handling processes required for genomic and proteomic analyses, reagent and specimen volume is minimized along with the size of the system. We demonstrate an automated microfluidic system capable of performing six multiplexed genomic and proteomic analyses simultaneously, by means of an integrated electrochemical sensor and embedded controls. (JALA 2009;14:407-12)
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