Journal
JOURNAL OF INFECTION IN DEVELOPING COUNTRIES
Volume 3, Issue 7, Pages 484-490Publisher
J INFECTION DEVELOPING COUNTRIES
DOI: 10.3855/jidc.465
Keywords
DNA adenine methylase; Pathogenesis; Salmonella enterica
Categories
Funding
- Agencia Nacional de Promocion a la Ciencia y Tecnologia [PICT-2006-00407]
- Universidad de Buenos Aires (UBACyT), Argentina [M608, M009]
Ask authors/readers for more resources
Dam methylation is an essential factor involved in the virulence of an increasing number of bacterial pathogens including Salmonella enterica. Lack of Dam methylation causes severe attenuation in animal models. It has been proposed that dysregulation of Dam activity is potentially a general strategy for the generation of vaccines against bacterial pathogens. In this review, we focus our attention on the role of methylation by Dam protein in regulating bacterial gene expression and virulence in Salmonella enterica.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available