Journal
INTERFACE FOCUS
Volume 4, Issue 5, Pages -Publisher
ROYAL SOC
DOI: 10.1098/rsfs.2014.0009
Keywords
sleep; aging; resilience pain; depression; mortality; inflammation
Categories
Funding
- National Institute of Aging [R01-AG034588]
- National Institutes of Health [R01-CA119159, R01-HL079955, R01 HL095799, P30-AG028748, UL RR 033176]
- Cousins Center for Psychoneuroimmunology
- UCLA Claude D. Pepper Older Americans Independence Center
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Sleep quality is important to health, and increasingly viewed as critical in promoting successful, resilient aging. In this review, the interplay between sleep and mental and physical health is considered with a focus on the role of inflammation as a biological pathway that translates the effects of sleep on risk of depression, pain and chronic disease risk in aging. Given that sleep regulates inflammatory biologic mechanisms with effects on mental and physical health outcomes, the potential of interventions that target sleep to reduce inflammation and promote health in aging is also discussed.
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