4.1 Article

Diarrhea, bacteremia and multiorgan dysfunction due to an extraintestinal pathogenic Escherichia coli strain with enteropathogenic E. coli genes

Journal

PATHOGENS AND DISEASE
Volume 73, Issue 8, Pages -

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/femspd/ftv076

Keywords

case report; comparative genomics; virulence factors; type 3 secretion; hemolysin

Funding

  1. Public Health Service grants from the National Institute of Allergy and Infectious Diseases [U19 AI090873, U19 AI110820]

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A 55-year-old man with well-controlled HIV had severe diarrhea for 3 weeks and developed multiorgan dysfunction and bacteremia due to Escherichia coli. The genome of the patient's isolate had features characteristic of extraintestinal pathogenic E. coli and genes distantly related to those defining enteropathogenic E. coli.

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