Journal
GREEN CHEMISTRY LETTERS AND REVIEWS
Volume 3, Issue 2, Pages 83-87Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/17518250903567246
Keywords
polyethylene glycol; 2-amino-4H-chromenes; alpha-naphthol; one-pot synthesis; aldehyde
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Polyethylene glycol-400 has been found to be a recyclable and rapid reaction medium for the synthesis of 2-amino-4H-chromenesby the condensation of aromatic aldehyde, malononitrile, and alpha-naphthol. This method gives remarkable advantages such as simple work up, high yields, and a greener method by avoiding toxic catalyst and hazardous solvents.
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