4.5 Article

Knoevenagel reaction: alum-mediated efficient green condensation of active methylene compounds with arylaldehydes

Journal

GREEN CHEMISTRY LETTERS AND REVIEWS
Volume 2, Issue 3, Pages 189-192

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/17518250903260925

Keywords

alum; active methylene compounds; Knoevenagel products

Funding

  1. Council of Scientific and Industrial Research (CSIR), New Delhi, India
  2. Indian National Science Academy (INSA), New Delhi, India

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A solvent-free stirred mixture of active methylene compounds, arylaldehyde and 10 mol% alum at 80 degrees C afforded Knoevenagel products in excellent yields. The use of a green catalyst, the solvent-free conditions, and shorter reaction times are the main features of this efficient protocol. [GRAPHICS] .

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