Journal
CELL ADHESION & MIGRATION
Volume 6, Issue 2, Pages 126-130Publisher
TAYLOR & FRANCIS INC
DOI: 10.4161/cam.18932
Keywords
-
Categories
Funding
- Damon Runyon Cancer Research Foundation
Ask authors/readers for more resources
The family of Eph tyrosine kinase receptors is an important part of signaling pathways involved in development, tissue homeostasis and tumorigenesis. Binding and activation of the receptors by their ligands, the ephrins, result in bidirectional signaling into both receptor and ligand expressing cells. Adult stem cell niches and tumors frequently express receptors and ligands, although their function is only beginning to be understood. Thus, Eph receptors and ephrins have become important molecules for understanding basic biological processes as well as tumorigenesis, and are promising targets for potential therapeutic intervention in human disease.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available