Journal
CANCER DISCOVERY
Volume 3, Issue 4, Pages 384-387Publisher
AMER ASSOC CANCER RESEARCH
DOI: 10.1158/2159-8290.CD-13-0042
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Funding
- NIH [DK047700, DK073338]
- University of North Carolina at Chapel Hill
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At a simplistic level, colorectal cancer arises from mutations in various proto-oncogenes and tumor suppressor genes. Aside from genetically inherited factors, environmental, lifestyle, and dietary habits have all been identified as risk agents promoting mutational events leading to the development of colorectal cancer. This In Focus presents evidence that the intestinal endogenous bacterial community represents a risk factor for the development of colorectal cancer. (C) 2013 AACR.
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