Journal
CANCER DISCOVERY
Volume 2, Issue 11, Pages 974-975Publisher
AMER ASSOC CANCER RESEARCH
DOI: 10.1158/2159-8290.CD-12-0432
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Miyamoto and colleagues present data that prostate-specific antigen/prostate-specific membrane antigen (PSA/PSMA)-based measurements of androgen receptor (AR) signaling in circulating tumor cells (CTC) enable real-time quantitative monitoring of intratumoral AR signaling. This finding indicates that measuring AR signaling within CTCs may help to guide therapy in metastatic prostate cancer and highlights the use of CTCs as liquid biopsy. Cancer Discov; 2(11); 974-5. (C) 2012 AACR. Commentary on Miyamoto et al., p. 995 (6).
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