Journal
BIOMEDICAL OPTICS EXPRESS
Volume 3, Issue 7, Pages 1662-1669Publisher
OPTICAL SOC AMER
DOI: 10.1364/BOE.3.001662
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Funding
- Cancer Prevention and Research Institute of Texas [RP120558]
- National Science Foundation Partnerships for Research and Education in Materials (PREM) [DMR-0934218]
- Northwestern University MRSEC
- Direct For Mathematical & Physical Scien
- Division Of Materials Research [934218] Funding Source: National Science Foundation
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Fluorescent nanodiamonds (FNDs) have drawn much attention in recent years for biomedical imaging applications due to their desired physical properties including excellent photostability, high biocompatibility, extended far-red fluorescence emission, and ease of surface functionalization. Here we explore a new feature of FNDs, i.e.their photoacoustic emission capability, which may lead to potential applications of using FNDs as a dual imaging contrast agent for combined fluorescence and photoacoustic imaging modalities. We observed significant enhancement of photoacoustic emission from FNDs when they were conjugated with gold nanoparticles (GNPs). (C) 2012 Optical Society of America
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