Journal
ACS COMBINATORIAL SCIENCE
Volume 15, Issue 9, Pages 519-524Publisher
AMER CHEMICAL SOC
DOI: 10.1021/co400086u
Keywords
MCRs; multicomponent reactions; three-component reaction; 2-aminopyridine; 4H-pyrido[1,2-a]pyrimidine
Funding
- National Natural Science Foundation of China [20902036, 81072526]
- Basic Scientific Research Fund of Jilin University
- Changchun Discovery Sciences, Ltd.
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A one-pot three-component reaction, involving condensation of 2-aminopyridines, aldehydes, and ketones/aldehydes under trifluoromethanesulfonic acid catalysis, provides, rapid access to highly substituted novel 4H-pyrido[1,2-a]pyrimidines.
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