Journal
ACS COMBINATORIAL SCIENCE
Volume 13, Issue 6, Pages 579-633Publisher
AMER CHEMICAL SOC
DOI: 10.1021/co200007w
Keywords
materials science; combinatorial and high-throughput (CHT) experimentation; electronic and functional materials; polymer-based industrial coatings; sensing materials; biomaterials
Funding
- GE
- National Institute of Standards and Technology Advanced Technology [70NANB9H3038]
- U.S. Department of Energy [DEFC07-01ID14093, DE-AC26-01NT41188]
- ONR-MURI [NN00014-06-1-1176]
- National Science Foundation [PHY-CDI-09-41576, CMMI-ARI-09-389018, CCF-AF-09-17202]
- Air Force Office of Scientific Research [FA9550-06-10501, FA9550-08-1-0316]
- Army Research Office [W911NF-10-1-0397]
- DARPA Center for Interfacial Engineering for MEMS (CIEMS) [1891874036790B]
- Federal Ministry of Education and Research BMBF
- German Research Foundation DFG
- NSF MRSEC DMR [0520471]
- ARO [W911NF-07-1-0410]
- ONR [N000140610530]
- Office of Naval Research [N00014-5-1-0822, N00014-6-1-0952, N00014-7-1-1099, N00014-8-1-1149, N00014-9-1-1193]
- Direct For Mathematical & Physical Scien
- Division Of Materials Research [0520471] Funding Source: National Science Foundation
- Direct For Mathematical & Physical Scien
- Division Of Physics [0941576] Funding Source: National Science Foundation
Ask authors/readers for more resources
Rational materials design based on prior knowledge is attractive because it promises to avoid time-consuming synthesis and testing of numerous materials candidates. However with the increase of complexity of materials, the scientific ability for the rational materials design becomes progressively limited. As a result of this complexity combinatorial and high-throughput (CHT) experimentation in materials science has been recognized as a new scientific approach to generate new knowledge. This review demonstrates the broad applicability of CHT experimentation technologies in discovery and optimization of new materials. We discuss general principles of CHT materials screening followed by the detailed discussion of high-throughput materials characterization approaches, advances in data, analysis/mining, and new materials developments facilitated by CHT experimentation. We critically analyze results of materials development in the areas most impacted by the CHT approaches, such as catalysis, electronic and functional materials, polymer-based industrial coatings, sensing materials, and biomaterials.
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