Journal
ACS COMBINATORIAL SCIENCE
Volume 14, Issue 1, Pages 38-43Publisher
AMER CHEMICAL SOC
DOI: 10.1021/co200128k
Keywords
combinatorial synthesis; ultrasound irradiation; multicomponent reaction; heterocycle; spiroindoline
Funding
- Foundation of the Natural Science Foundation of China [21072144]
- Natural Science Foundation of the Jiangsu Higher Education Institutions [10KJA150049]
- Jiangsu Higher Education Institutions
- Key Laboratory of Organic Synthesis of Jiangsu Province [KJS0812]
Ask authors/readers for more resources
An efficient one-pot synthesis of spiro[indoline-3,4'-pyrano[2,3-c]pyrazole] derivatives by four-component reaction of hydrazine, beta-keto ester, isatin, and malononitrile or ethyl cyanoacetate catalyzed by piperidine under ultrasound irradiation is described. This synthesis was confirmed to follow the group-assistant-purification chemistry (GAP) chemistry process, which can avoid traditional chromatography and recrystallization purifications.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
