Journal
ACS CATALYSIS
Volume 8, Issue 10, Pages 9120-9124Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acscatal.8b02954
Keywords
photoredox catalysis; nickel catalysis; cross-coupling; C-N bond formation; synthetic methods
Categories
Ask authors/readers for more resources
Medicinally relevant diarylamines are prepared through a photoredox-mediated dual catalytic nickel/ruthenium system from aryl azides and aryl electrophiles. Photoreduction of the aryl azide is proposed to proceed through an arylnickel-azide complex, which upon reduction and loss of nitrogen, generates a nickel(III) species capable of facile reductive elimination to afford the desired C-N bond formation. A variety of functionalized (hetero)aryl electrophiles are shown to participate in the coupling, including iodides, bromides, chlorides, and triflates. The reactions are simple to set up and are performed under ambient conditions, without the exclusion of oxygen or moisture.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available