Recent Advances in Iridium-Catalyzed Alkylation of C-H and N-H Bonds

Over the past few years, iridium complexes have been widely used in the direct functionalization of unactivated bonds. In the presence of iridium catalysts, inactive C-H and N-H bonds have been transformed into C-C and N-C bonds in dehydrative alkylation using alcohols, allylation using allyl carbonates, and alkylation using alkenes. Enantioselective variants of some reactions have also been reported.