Related references
Note: Only part of the references are listed.An In-Situ Study of the Modulation of the Mechano-Kinetic Parameters of the Slow Isoform of Muscle Myosin II by the Heart Drug Omecamtiv Mecarbil
Marco Caremani et al.
BIOPHYSICAL JOURNAL (2018)
Controlling load-dependent kinetics of β-cardiac myosin at the single-molecule level
Chao Liu et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
Electro-optic deflectors deliver advantages over acousto-optical deflectors in a high resolution, ultra-fast force-clamp optical trap
Michael S. Woody et al.
OPTICS EXPRESS (2018)
Controlling load-dependent kinetics of β-cardiac myosin at the single-molecule level
Chao Liu et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
Omecamtiv Mecarbil Enhances the Duty Ratio of Human -Cardiac Myosin Resulting in Increased Calcium Sensitivity and Slowed Force Development in Cardiac Muscle
Anja M. Swenson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Heart failure drug changes the mechanoenzymology of the cardiac myosin powerstroke
John A. Rohde et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Mechanistic and structural basis for activation of cardiac myosin force production by omecamtiv mecarbil
Vicente J. Planelles-Herrero et al.
NATURE COMMUNICATIONS (2017)
Allosteric modulation of cardiac myosin dynamics by omecamtiv mecarbil
Shaima Hashem et al.
PLOS COMPUTATIONAL BIOLOGY (2017)
The molecular basis of thin filament activation: from single molecule to muscle
Thomas Longyear et al.
SCIENTIFIC REPORTS (2017)
Omecamtiv Mecarbil Abolishes Length-Mediated Increase in Guinea Pig Cardiac Myofiber Ca2+ Sensitivity
Sampath K. Gollapudi et al.
BIOPHYSICAL JOURNAL (2017)
MEMLET: An Easy-to-Use Tool for Data Fitting and Model Comparison Using Maximum-Likelihood Estimation
Michael S. Woody et al.
BIOPHYSICAL JOURNAL (2016)
Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure (COSMIC-HF): a phase 2, pharmacokinetic, randomised, placebo-controlled trial
John R. Teerlink et al.
LANCET (2016)
Omecamtiv Mecarbil Modulates the Kinetic and Motile Properties of Porcine beta-Cardiac Myosin
Yingying Liu et al.
BIOCHEMISTRY (2015)
The novel cardiac myosin activator omecamtiv mecarbil increases the calcium sensitivity of force production in isolated cardiomyocytes and skeletal muscle fibres of the rat
L. Nagy et al.
BRITISH JOURNAL OF PHARMACOLOGY (2015)
Population pharmacokinetic-pharmacodynamic modeling of omecamtiv mecarbil, a cardiac myosin activator, in healthy volunteers and patients with stable heart failure
Thuy Vu et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2015)
Molecular effects of the myosin activator omecamtiv mecarbil on contractile properties of skinned myocardium lacking cardiac myosin binding protein-C
Ranganath Mamidi et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2015)
Structural basis for drug-induced allosteric changes to human β-cardiac myosin motor activity
Donald A. Winkelmann et al.
NATURE COMMUNICATIONS (2015)
Ensemble Force Changes that Result from Human Cardiac Myosin Mutations and a Small-Molecule Effector
Tural Aksel et al.
CELL REPORTS (2015)
Inherent Force-Dependent Properties of β-Cardiac Myosin Contribute to the Force-Velocity Relationship of Cardiac Muscle
Michael J. Greenberg et al.
BIOPHYSICAL JOURNAL (2014)
Inotropes
Gary S. Francis et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2014)
Muscle activation described with a differential equation model for large ensembles of locally coupled molecular motors
Sam Walcott
PHYSICAL REVIEW E (2014)
Myosin IC generates power over a range of loads via a new tension-sensing mechanism
Michael J. Greenberg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The effects of the cardiac myosin activator, omecamtiv mecarbil, on cardiac function in systolic heart failure: a double-blind, placebo-controlled, crossover, dose-ranging phase 2 trial
John G. F. Cleland et al.
LANCET (2011)
Dose-dependent augmentation of cardiac systolic function with the selective cardiac myosin activator, omecamtiv mecarbil: a first-in-man study
John R. Teerlink et al.
LANCET (2011)
Cardiac Myosin Activation: A Potential Therapeutic Approach for Systolic Heart Failure
Fady I. Malik et al.
SCIENCE (2011)
Nonlinear Elasticity and an 8-nm Working Stroke of Single Myosin Molecules in Myofilaments
Motoshi Kaya et al.
SCIENCE (2010)
Single-molecule measurement of the stiffness of the rigor myosin head
Alexandre Lewalle et al.
BIOPHYSICAL JOURNAL (2008)
Myosin I can act as a molecular force sensor
Joseph M. Laakso et al.
SCIENCE (2008)
Force generation in single conventional actomyosin complexes under high dynamic load
Y Takagi et al.
BIOPHYSICAL JOURNAL (2006)
Reconciling the working strokes of a single head of skeletal muscle myosin estimated from laser-trap experiments and crystal structures
J Sleep et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Single-myosin crossbridge interactions with actin filaments regulated by troponin-tropomyosin
NM Kad et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Position control and optical manipulation for nanotechnology applications
M Capitanio et al.
EUROPEAN PHYSICAL JOURNAL B (2005)
Power spectrum analysis for optical tweezers
K Berg-Sorensen et al.
REVIEW OF SCIENTIFIC INSTRUMENTS (2004)
Share Paper
