4.8 Article

Carbon nanotube-liposome supramolecular nanotrains for intelligent molecular-transport systems

Journal

NATURE COMMUNICATIONS
Volume 3, Issue -, Pages -

Publisher

NATURE PORTFOLIO
DOI: 10.1038/ncomms2233

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Funding

  1. Kao Foundation for Arts and Sciences
  2. Japan Prize Foundation
  3. [23700568]
  4. Grants-in-Aid for Scientific Research [23700568] Funding Source: KAKEN

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Biological network systems, such as inter- and intra-cellular signalling systems, are handled in a sophisticated manner by the transport of molecular information. Over the past few decades, there has been a growing interest in the development of synthetic molecular-transport systems. However, several key technologies have not been sufficiently realized to achieve optimum performance of transportation methods. Here we show that a new type of supramolecular system comprising of carbon nanotubes and liposomes enables the directional transport and controlled release of carrier molecules, and allows an enzymatic reaction at a desired area. The study highlights important progress that has been made towards the development of biomimetic molecular-transport systems and various lab-on-a-chip applications, such as medical diagnosis, sensors, bionic computers and artificial biological networks.

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