Related references
Note: Only part of the references are listed.Aberrant T-lymphocyte development and function in mice overexpressing human soluble amyloid precursor protein-α : implications for autism
Antoinette R. Bailey et al.
FASEB JOURNAL (2012)
Presenilin-1 but not amyloid precursor protein mutations present in mouse models of Alzheimer's disease attenuate the response of cultured cells to γ-secretase modulators regardless of their potency and structure
Stefanie Hahn et al.
JOURNAL OF NEUROCHEMISTRY (2011)
CD45 Deficiency Drives Amyloid-β Peptide Oligomers and Neuronal Loss in Alzheimer's Disease Mice
Yuyan Zhu et al.
JOURNAL OF NEUROSCIENCE (2011)
Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimer's disease (vol 10, pg 187, 2011)
D. Kapogiannis et al.
LANCET NEUROLOGY (2011)
Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimer's disease
Dimitrios Kapogiannis et al.
LANCET NEUROLOGY (2011)
被撤回的出版物: SIRT1 Suppresses β-Amyloid Production by Activating the α-Secretase Gene ADAM10 (Retracted article. See vol. 158, pg. 959, 2014)
Gizem Donmez et al.
CELL (2010)
Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate α-secretase activity
Minji Kim et al.
HUMAN MOLECULAR GENETICS (2009)
Neuroprotective Secreted Amyloid Precursor Protein Acts by Disrupting Amyloid Precursor Protein Dimers
Matthias Gralle et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Oxidative stress promotes JNK-dependent amyloidogenic processing of normally expressed human APP by differential modification of α-, β- and γ-secretase expression
Ricardo Quiroz-Baez et al.
NEUROCHEMISTRY INTERNATIONAL (2009)
Genetic deletion of BACE1 in mice affects remyelination of sciatic nerves
Xiangyou Hu et al.
FASEB JOURNAL (2008)
Hydrogen peroxide promotes Aβ production through JNK-dependent activation of γ-secretase
Chengyong Shen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Homophilic interactions of the amyloid precursor protein (APP) ectodomain are regulated by the loop region and affect β-secretase cleavage of APP
Daniela Kaden et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
Ganesh M. Shankar et al.
NATURE MEDICINE (2008)
Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1
Tracy L. Young-Pearse et al.
NEURAL DEVELOPMENT (2008)
ADAM-10 over-expression increases cortical synaptogenesis
Karen F. S. Bell et al.
NEUROBIOLOGY OF AGING (2008)
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
Jill C. Milne et al.
NATURE (2007)
Inhibition of amyloid β-peptide production by blockage of β-secretase cleavage site of amyloid precursor protein
Chan Hyun Na et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases β-cleavage of amyloid precursor protein and amyloid-β production in vivo
Ishrut Hussain et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Bace1 modulates myelination in the central and peripheral nervous system
Xiangyou Hu et al.
NATURE NEUROSCIENCE (2006)
Control of peripheral nerve myelination by the β-secretase BACE1
Michael Willem et al.
SCIENCE (2006)
Effects of anoxia and hypoxia on amyloid precursor protein processing in cerebral microvascular smooth muscle cells
Ilene D. Auerbach et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2006)
Vascular remodeling versus amyloid β-induced oxidative stress in the cerebrovascular dysfunctions associated with Alzheimer's disease
XK Tong et al.
JOURNAL OF NEUROSCIENCE (2005)
β subunits of voltage-gated sodium channels are novel substrates of β-site amyloid precursor protein-cleaving enzyme (BACE1) and γ-secretase
HK Wong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The low density lipoprotein receptor-related protein (LRP) is a novel β-secretase (BACE1) substrate
CAF von Arnim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
β-Site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways
E Tamagno et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSw mice resulting in tau phosphorylation and loss of hippocampal neurons:: Support for the amyloid hypothesis
TD Stein et al.
JOURNAL OF NEUROSCIENCE (2004)
Neuronal membrane cholesterol loss enhances amyloid pepticle generation
J Abad-Rodriguez et al.
JOURNAL OF CELL BIOLOGY (2004)
Altered processing of the amyloid precursor protein and decreased expression of ADAM 10 by chronic hypoxia in SH-SY5Y: no role for the stress-activated JNK and p38 signalling pathways
NJ Webster et al.
MOLECULAR BRAIN RESEARCH (2004)
The cell adhesion protein P-selectin glycoprotein ligand-1 is a substrate for the aspartyl protease BACE1
SF Lichtenthaler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Characterization of the ectodomain shedding of the β-site amyloid precursor protein-cleaving enzyme 1 (BACE1)
I Hussain et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
γ-secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2
WT Kimberly et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Lower cognitive function in the presence of obesity and hypertension: the Framingham heart study
MF Elias et al.
INTERNATIONAL JOURNAL OF OBESITY (2003)
Altered processing of amyloid precursor protein in the human neuroblastoma SH-SY5Y by chronic hypoxia
NJ Webster et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Medicine - The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
J Hardy et al.
SCIENCE (2002)
Cholesterol-dependent γ-secretase activity in buoyant cholesterol-rich membrane microdomains
S Wahrle et al.
NEUROBIOLOGY OF DISEASE (2002)
Alzheimer's β-secretase, β-site amyloid precursor protein-cleaving enzyme, is responsible for cleavage secretion of a Golgi-resident sialyltransferase
S Kitazume et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Diabetes mellitus and risk of Alzheimer's disease and dementia with stroke in a multiethnic cohort
JA Luchsinger et al.
AMERICAN JOURNAL OF EPIDEMIOLOGY (2001)
The transmembrane domain of the Alzheimer's β-secretase (BACE1) determines its late Golgi localization and access to β-amyloid precursor protein (APP) substrate
RQ Yan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Post-translational processing of β-secretase (β-amyloid-converting enzyme) and its ectodomain shedding -: The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-β production
S Benjannet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Share Paper
