4.8 Review

Transcriptional and epigenetic regulation of autophagy in aging

Related references

Note: Only part of the references are listed.
Article Cell Biology

Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB

Diego L. Medina et al.

NATURE CELL BIOLOGY (2015)

Review Cell Biology

Cracking the survival code Autophagy-related histone modifications

Jens Fullgrabe et al.

AUTOPHAGY (2014)

Article Pharmacology & Pharmacy

Regulation of autophagy by miR-30d impacts sensitivity of anaplastic thyroid carcinoma to cisplatin

Y. Zhang et al.

BIOCHEMICAL PHARMACOLOGY (2014)

Review Cell Biology

Autophagy regulation by nutrient signaling

Ryan C. Russell et al.

CELL RESEARCH (2014)

Review Cell Biology

The machinery of macroautophagy

Yuchen Feng et al.

CELL RESEARCH (2014)

Article Biochemistry & Molecular Biology

Transcriptional Regulation by Pho23 Modulates the Frequency of Autophagosome Formation

Meiyan Jin et al.

CURRENT BIOLOGY (2014)

Article Medicine, Research & Experimental

Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB

Vinicia A. Polito et al.

EMBO MOLECULAR MEDICINE (2014)

Article Biochemistry & Molecular Biology

Regulation of Autophagy by Cytosolic Acetyl-Coenzyme A

Guillermo Marino et al.

MOLECULAR CELL (2014)

Review Cell Biology

The return of the nucleus: transcriptional and epigenetic control of autophagy

Jens Fullgrabe et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)

Review Cell Biology

Lysosome: regulator of lipid degradation pathways

Carmine Settembre et al.

TRENDS IN CELL BIOLOGY (2014)

Review Genetics & Heredity

Sirtuins: guardians of mammalian healthspan

William Giblin et al.

TRENDS IN GENETICS (2014)

Review Pharmacology & Pharmacy

Small molecule SIRT1 activators for the treatment of aging and age-related diseases

Basil P. Hubbard et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2014)

Article Cell Biology

AMPK Modulates Tissue and Organismal Aging in a Non-Cell-Autonomous Manner

Matthew Ulgherait et al.

CELL REPORTS (2014)

Article Genetics & Heredity

Lifespan Extension by Methionine Restriction Requires Autophagy-Dependent Vacuolar Acidification

Christoph Ruckenstuhl et al.

PLOS GENETICS (2014)

Article Biochemistry & Molecular Biology

mir-30d Regulates multiple genes in the autophagy pathway and impairs autophagy process in human cancer cells

Xiaojun Yang et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)

Review Biochemistry & Molecular Biology

Transcriptional Regulation and Its Misregulation in Disease

Tong Ihn Lee et al.

Article Cell Biology

Up-to-date membrane biogenesis in the autophagosome formation

Maho Hamasaki et al.

CURRENT OPINION IN CELL BIOLOGY (2013)

Article Oncology

Autophagic lysosome reformation

Yang Chen et al.

EXPERIMENTAL CELL RESEARCH (2013)

Review Biochemistry & Molecular Biology

Protein breakdown in muscle wasting: Role of autophagy-lysosome and ubiquitin-proteasome

Marco Sandri

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2013)

Article Cell Biology

Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases

Constance S. Petit et al.

JOURNAL OF CELL BIOLOGY (2013)

Article Biochemistry & Molecular Biology

Epigenetic Regulation of Autophagy by the Methyltransferase G9a

Amaia Artal-Martinez de Narvajas et al.

MOLECULAR AND CELLULAR BIOLOGY (2013)

Article Biochemistry & Molecular Biology

The Folliculin Tumor Suppressor Is a GAP for the RagC/D GTPases That Signal Amino Acid Levels to mTORC1

Zhi-Yang Tsun et al.

MOLECULAR CELL (2013)

Article Biochemistry & Molecular Biology

ZKSCAN3 Is a Master Transcriptional Repressor of Autophagy

Santosh Chauhan et al.

MOLECULAR CELL (2013)

Article Multidisciplinary Sciences

The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy

Jens Fullgrabe et al.

NATURE (2013)

Article Cell Biology

TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop

Carmine Settembre et al.

NATURE CELL BIOLOGY (2013)

Article Cell Biology

MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability

Eyleen J. O'Rourke et al.

NATURE CELL BIOLOGY (2013)

Article Cell Biology

DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity

Christian G. Riedel et al.

NATURE CELL BIOLOGY (2013)

Review Cell Biology

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

Carmine Settembre et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)

Review Cell Biology

Amino acid signalling upstream of mTOR

Jenna L. Jewell et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)

Article Geriatrics & Gerontology

Autophagy induced by the class III histone deacetylase Sirt1 prevents prion peptide neurotoxicity

Jae-Kyo Jeong et al.

NEUROBIOLOGY OF AGING (2013)

Article Multidisciplinary Sciences

MIR376A Is a Regulator of Starvation-Induced Autophagy

Gozde Korkmaz et al.

PLOS ONE (2013)

Review Oncology

Regulation of autophagy by stress-responsive transcription factors

Federico Pietrocola et al.

SEMINARS IN CANCER BIOLOGY (2013)

Article Multidisciplinary Sciences

Overexpression of Atg5 in mice activates autophagy and extends lifespan

Jong-Ok Pyo et al.

NATURE COMMUNICATIONS (2013)

Review Biochemistry & Molecular Biology

mTOR Signaling in Growth Control and Disease

Mathieu Laplante et al.

Article Cell Biology

TOR Signaling and Rapamycin Influence Longevity by Regulating SKN-1/Nrf and DAF-16/FoxO

Stacey Robida-Stubbs et al.

CELL METABOLISM (2012)

Article Biochemistry & Molecular Biology

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

Carmine Settembre et al.

EMBO JOURNAL (2012)

Article Biochemistry & Molecular Biology

Global heterochromatin loss A unifying theory of aging?

Amy Tsurumi et al.

EPIGENETICS (2012)

Article Physiology

Modulation of autophagy and ubiquitin-proteasome pathways during ultra-endurance running

Cecile Jamart et al.

JOURNAL OF APPLIED PHYSIOLOGY (2012)

Article Cell Biology

MicroRNAs and their roles in aging

Thalyana Smith-Vikos et al.

JOURNAL OF CELL SCIENCE (2012)

Review Biochemistry & Molecular Biology

Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks

Sebastian Alers et al.

MOLECULAR AND CELLULAR BIOLOGY (2012)

Article Multidisciplinary Sciences

The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila

Nan Liu et al.

NATURE (2012)

Article Multidisciplinary Sciences

Increased proteasome activity in human embryonic stem cells is regulated by PSMD11

David Vilchez et al.

NATURE (2012)

Article Multidisciplinary Sciences

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

Congcong He et al.

NATURE (2012)

Article Multidisciplinary Sciences

RPN-6 determines C. elegans longevity under proteotoxic stress conditions

David Vilchez et al.

NATURE (2012)

Editorial Material Cell Biology

FOXOphagy path to inducing stress resistance and cell survival

Marco Sandri

NATURE CELL BIOLOGY (2012)

Article Biochemistry & Molecular Biology

The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis

Agnes Roczniak-Ferguson et al.

SCIENCE SIGNALING (2012)

Review Cell Biology

Histone methylation makes its mark on longevity

Shuo Han et al.

TRENDS IN CELL BIOLOGY (2012)

Review Endocrinology & Metabolism

Lessons from C. elegans: signaling pathways for longevity

Louis R. Lapierre et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2012)

Review Cell Biology

Polyamines in aging and disease

Nadege Minois et al.

AGING-US (2011)

Review Cell Biology

Selective autophagy mediated by autophagic adapter proteins

Terje Johansen et al.

AUTOPHAGY (2011)

Review Biochemistry & Molecular Biology

Autophagy and Aging

David C. Rubinsztein et al.

Article Cell Biology

Modulation of Longevity and Tissue Homeostasis by the Drosophila PGC-1 Homolog

Michael Rera et al.

CELL METABOLISM (2011)

Article Biochemistry & Molecular Biology

Autophagy and Lipid Metabolism Coordinately Modulate Life Span in Germline-less C. elegans

Louis R. Lapierre et al.

CURRENT BIOLOGY (2011)

Article Cell Biology

Transcriptional Activation of Lysosomal Exocytosis Promotes Cellular Clearance

Diego L. Medina et al.

DEVELOPMENTAL CELL (2011)

Article Biochemistry & Molecular Biology

Regulation of TFEB and V-ATPases by mTORC1

Samuel Pena-Llopis et al.

EMBO JOURNAL (2011)

Article Biochemistry & Molecular Biology

microRNA-101 is a potent inhibitor of autophagy

Lisa B. Frankel et al.

EMBO JOURNAL (2011)

Article Biochemistry & Molecular Biology

Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C. elegans

Wei Niu et al.

GENOME RESEARCH (2011)

Article Biochemistry & Molecular Biology

SUV420H2-Mediated H4K20 Trimethylation Enforces RNA Polymerase II Promoter-Proximal Pausing by Blocking hMOF-Dependent H4K16 Acetylation

Priya Kapoor-Vazirani et al.

MOLECULAR AND CELLULAR BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Resveratrol-Activated AMPK/SIRT1/Autophagy in Cellular Models of Parkinson's Disease

Yuncheng Wu et al.

NEUROSIGNALS (2011)

Article Multidisciplinary Sciences

TFEB Links Autophagy to Lysosomal Biogenesis

Carmine Settembre et al.

SCIENCE (2011)

Article Cell Biology

Chromatin remodeling in the aging genome of Drosophila

Jason G. Wood et al.

AGING CELL (2010)

Editorial Material Cell Biology

The life span-prolonging effect of sirtuin-1 is mediated by autophagy

Eugenia Morselli et al.

AUTOPHAGY (2010)

Article Biochemistry & Molecular Biology

FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis during Aging

Fabio Demontis et al.

Article Biochemistry & Molecular Biology

MicroRNAs Both Promote and Antagonize Longevity in C-elegans

Alexandre de Lencastre et al.

CURRENT BIOLOGY (2010)

Article Biochemistry & Molecular Biology

Mitochondrial fission and remodelling contributes to muscle atrophy

Vanina Romanello et al.

EMBO JOURNAL (2010)

Article Medicine, Research & Experimental

Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney

Shinji Kume et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Review Biochemistry & Molecular Biology

Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

Shomit Sengupta et al.

MOLECULAR CELL (2010)

Review Biochemistry & Molecular Biology

Autophagy and the Integrated Stress Response

Guido Kroemer et al.

MOLECULAR CELL (2010)

Review Multidisciplinary Sciences

The genetics of ageing

Cynthia J. Kenyon

NATURE (2010)

Review Cell Biology

Autophagy in mammalian development and differentiation

Noboru Mizushima et al.

NATURE CELL BIOLOGY (2010)

Review Neurosciences

Autophagy gone awry in neurodegenerative diseases

Esther Wong et al.

NATURE NEUROSCIENCE (2010)

Article Multidisciplinary Sciences

Polyamine pathway contributes to the pathogenesis of Parkinson disease

Nicole M. Lewandowski et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Biochemistry & Molecular Biology

Widespread Protein Aggregation as an Inherent Part of Aging in C. elegans

Della C. David et al.

PLOS BIOLOGY (2010)

Article Genetics & Heredity

Essential Functions of the Histone Demethylase Lid

Ling Li et al.

PLOS GENETICS (2010)

Article Cell Biology

Autophagy genes mediate the effect of calcineurin on life span in C. elegans

Meenakshi Dwivedi et al.

AUTOPHAGY (2009)

Review Cell Biology

Evolution of Atg1 function and regulation

Edmond Y. Chan et al.

AUTOPHAGY (2009)

Review Biochemistry & Molecular Biology

Autophagy: A lysosomal degradation pathway with a central role in health and disease

Eeva-Liisa Eskelinen et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)

Article Biochemistry & Molecular Biology

A Multiparameter Network Reveals Extensive Divergence between C. elegans bHLH Transcription Factors

Christian A. Grove et al.

Review Cell Biology

SIRT1: Regulation of longevity via autophagy

Antero Salminen et al.

CELLULAR SIGNALLING (2009)

Article Geriatrics & Gerontology

Polyamine-rich food decreases age-associated pathology and mortality in aged mice

Kuniyasu Soda et al.

EXPERIMENTAL GERONTOLOGY (2009)

Article Biochemistry & Molecular Biology

FoxO Transcription Factors Promote Autophagy in Cardiomyocytes

Arunima Sengupta et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Multidisciplinary Sciences

A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants

Sean P. Curran et al.

NATURE (2009)

Article Cell Biology

Induction of autophagy by spermidine promotes longevity

Tobias Eisenberg et al.

NATURE CELL BIOLOGY (2009)

Article Multidisciplinary Sciences

Autophagy genes protect against Salmonella typhimurium infection and mediate insulin signaling-regulated pathogen resistance

Kailiang Jia et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Multidisciplinary Sciences

Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging

Anat Ben-Zvi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Multidisciplinary Sciences

A Gene Network Regulating Lysosomal Biogenesis and Function

Marco Sardiello et al.

SCIENCE (2009)

Review Biochemistry & Molecular Biology

Regulation of the aging process by autophagy

Antero Salminen et al.

TRENDS IN MOLECULAR MEDICINE (2009)

Article Cell Biology

Dynamics and function of PtdIns(3)P in autophagy

Keisuke Obara et al.

AUTOPHAGY (2008)

Article Biochemistry & Molecular Biology

The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging

Karyn L. Sheaffer et al.

CURRENT BIOLOGY (2008)

Article Chemistry, Physical

Spermine binding to Parkinson's protein α-synuclein and its disease-related A30P and A53T mutants

Megan Grabenauer et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2008)

Review Biochemistry & Molecular Biology

The FoxO code

D. R. Calnan et al.

ONCOGENE (2008)

Article Genetics & Heredity

A role for autophagy in the extension of lifespan by dietary restriction in C-elegans

Malene Hansen et al.

PLOS GENETICS (2008)

Article Multidisciplinary Sciences

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

In Hye Lee et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

miR-34a repression of SIRT1 regulates apoptosis

Munekazu Yamakuchi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

Fat Metabolism Links Germline Stem Cells and Longevity in C. elegans

Meng C. Wang et al.

SCIENCE (2008)

Article Multidisciplinary Sciences

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

Yasemin Sancak et al.

SCIENCE (2008)

Article Genetics & Heredity

C-elegans model identifies genetic modifiers of α-synuclein inclusion formation during aging

Tjakko J. van Ham et al.

PLOS GENETICS (2008)

Article Cell Biology

FoxO3 controls autophagy in skeletal muscle in vivo

Cristina Mammucari et al.

CELL METABOLISM (2007)

Article Biochemistry & Molecular Biology

The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor

Eric L. Greer et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C-elegans

Eric L. Greer et al.

CURRENT BIOLOGY (2007)

Article Multidisciplinary Sciences

PHA-4/Foxa mediates diet-restriction-induced longevity of C-elegans

Siler H. Panowski et al.

NATURE (2007)

Article Cell Biology

Autophagy regulates ageing in C-elegans

Enter S. Hars et al.

AUTOPHAGY (2007)

Article Geriatrics & Gerontology

The search for DAF-16/FOXO transcriptional targets: Approaches and discoveries

Coleen T. Murphy

EXPERIMENTAL GERONTOLOGY (2006)

Article Multidisciplinary Sciences

Loss of autophagy in the central nervous system causes neurodegeneration in mice

Masaaki Komatsu et al.

NATURE (2006)

Article Cell Biology

Modulated microRNA expression during adult lifespan in Caenorhabditis elegans

Carolina Ibanez-Ventoso et al.

AGING CELL (2006)

Article Biochemistry & Molecular Biology

The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases

RL Hurley et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Cell Biology

Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins

Y Zhang et al.

NATURE CELL BIOLOGY (2003)

Article Cell Biology

Rheb promotes cell growth as a component of the insulin/TOR signalling network

LJ Saucedo et al.

NATURE CELL BIOLOGY (2003)

Article Biochemistry & Molecular Biology

Cellular polyamines promote the aggregation of α-synuclein

T Antony et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Multidisciplinary Sciences

Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development

E Steingrimsson et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)