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Current and potential epigenetic targets in multiple myeloma

Journal

EPIGENOMICS
Volume 6, Issue 2, Pages 215-228

Publisher

FUTURE MEDICINE LTD
DOI: 10.2217/epi.14.12

Keywords

bromodomain inhibitor; chromatin; DNA methyltransferase inhibitor; histone deacetylase inhibitor; histone demethylase inhibitor; histone methyltransferase inhibitor; multiple myeloma

Funding

  1. Myeloma UK
  2. Cancer Research UK [12103] Funding Source: researchfish

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Despite recent advances in therapy, subgroups of multiple myeloma continue to have a poor prognosis. Numerous epigenetic changes have been described and occur as both etiologic and secondary events, making myeloma a good disease in which to understand the role of epigenetic therapies. Here, we describe a number of current and potential epigenetic targets in myeloma.

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