Journal
JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH
Volume 4, Issue 3, Pages 238-244Publisher
SPRINGER
DOI: 10.1007/s12265-011-9262-6
Keywords
Heart failure; Cardiomyopathy; Genetics; Mechanosensation
Funding
- DFG [Kn 448/9-1, Kn448/10-1]
- Fritz Thyssen Foundation
- British Heart Foundation
Ask authors/readers for more resources
Mechanosensation (the ultimate conversion of a mechanical stimulus into a biochemical signal) as well as mechanotransduction (transmission of mechanically induced signals) belong to the most fundamental processes in biology. These effects, because of their dynamic nature, are particularly important for the cardiovascular system. Therefore, it is not surprising that defects in cardiac mechanosensation, are associated with various types of cardiomyopathy and heart failure. However, our current knowledge regarding the genetic basis of impaired mechanosensation in the cardiovascular system is beginning to shed light on this subject and is at the centre of this brief review.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available