4.7 Article

Rapamycin reverses insulin resistance (IR) in high-glucose medium without causing IR in normoglycemic medium

Related references

Note: Only part of the references are listed.
Article Cell Biology

Gerometabolites The pseudohypoxic aging side of cancer oncometabolites

Javier A. Menendez et al.

CELL CYCLE (2014)

Article Cell Biology

M(o)TOR of pseudo-hypoxic state in aging Rapamycin to the rescue

Olga V. Leontieva et al.

CELL CYCLE (2014)

Editorial Material Cell Biology

Prolonged Rapamycin treatment led to beneficial metabolic switch

Yimin Fang et al.

AGING-US (2013)

Article Cell Biology

mTOR in aging, metabolism, and cancer

Marion Cornu et al.

CURRENT OPINION IN GENETICS & DEVELOPMENT (2013)

Article Biochemistry & Molecular Biology

Insulin Activates RSK (p90 Ribosomal S6 Kinase) to Trigger a New Negative Feedback Loop That Regulates Insulin Signaling for Glucose Metabolism

Nicolas Smadja-Lamere et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Pathology

Prevention of Age-Related Macular Degeneration-Like Retinopathy by Rapamycin in Rats

Nataliya G. Kolosova et al.

AMERICAN JOURNAL OF PATHOLOGY (2012)

Article Cell Biology

Hyper-mitogenic drive coexists with mitotic incompetence in senescent cells

Olga V. Leontieva et al.

CELL CYCLE (2012)

Editorial Material Cell Biology

Glutaminolysis feeds mTORC1

Raul V. Duran et al.

CELL CYCLE (2012)

Article Cell & Tissue Engineering

mTOR Inhibition Prevents Epithelial Stem Cell Senescence and Protects from Radiation-Induced Mucositis

Ramiro Iglesias-Bartolome et al.

CELL STEM CELL (2012)

Article Endocrinology & Metabolism

The Critical Role of Metabolic Pathways in Aging

Nir Barzilai et al.

DIABETES (2012)

Article Multidisciplinary Sciences

Hypoxia suppresses conversion from proliferative arrest to cellular senescence

Olga V. Leontieva et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Multidisciplinary Sciences

Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity

Dudley W. Lamming et al.

SCIENCE (2012)

Article Cell Biology

The purpose of the HIF-1/PHD feedback loop To limit mTOR-induced HIF-1α

Zoya N. Demidenko et al.

CELL CYCLE (2011)

Article Cell Biology

Rapamycin-induced glucose intolerance Hunger or starvation diabetes

Mikhail V. Blagosklonny

CELL CYCLE (2011)

Article Biochemistry & Molecular Biology

Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1)

Laura R. Pearce et al.

BIOCHEMICAL JOURNAL (2010)

Review Biochemistry & Molecular Biology

Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

Shomit Sengupta et al.

MOLECULAR CELL (2010)

Article Multidisciplinary Sciences

Paradoxical suppression of cellular senescence by p53

Zoya N. Demidenko et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Cell Biology

Growth and aging: a common molecular mechanism

Mikhail V. Blagosklonny et al.

AGING-US (2009)

Article Pharmacology & Pharmacy

Long-term Administration of Rapamycin Reduces Adiposity, but Impairs Glucose Tolerance in High-Fat Diet-fed KK/HlJ Mice

Geng-Ruei Chang et al.

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2009)

Article Biochemistry & Molecular Biology

mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells

Chong Chen et al.

SCIENCE SIGNALING (2009)

Article Immunology

Mammalian Target of Rapamycin and Diabetes: What Does the Current Evidence Tell Us?

B. Vodenik et al.

TRANSPLANTATION PROCEEDINGS (2009)

Article Cell Biology

Growth stimulation leads to cellular senescence when the cell cycle is blocked

Zoya N. Demidenko et al.

CELL CYCLE (2008)

Article Endocrinology & Metabolism

The role of mTOR in the adaptation and failure of β-cells in type 2 diabetes

G. Leibowitz et al.

DIABETES OBESITY & METABOLISM (2008)

Article Biochemistry & Molecular Biology

Enhanced activation of a nutrient-sensing pathway with age contributes to insulin resistance

Francine H. Einstein et al.

FASEB JOURNAL (2008)

Article Biochemistry & Molecular Biology

S6K Directly Phosphorylates IRS-1 on Ser-270 to Promote Insulin Resistance in Response to TNF-α Signaling through IKK2

Jin Zhang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Biphasic response of pancreatic β-cell mass to ablation of tuberous sclerosis complex 2 in mice

Yutaka Shigeyama et al.

MOLECULAR AND CELLULAR BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Activation of mammalian target of rapamycin complex 1 and insulin resistance induced by palmitate in hepatocytes

Sylvie Mordier et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Review Biochemistry & Molecular Biology

Upstream of the mammalian target of rapamycin: do all roads pass through mTOR?

M. N. Corradetti et al.

ONCOGENE (2006)

Review Biochemistry & Molecular Biology

TOR signaling in growth and metabolism

S Wullschleger et al.

Review Biochemistry & Molecular Biology

TOR signaling in growth and metabolism

Stephan Wullschleger et al.

Review Biochemistry & Molecular Biology

Restraining PI3K: mTOR signalling goes back to the membrane

LS Harrington et al.

TRENDS IN BIOCHEMICAL SCIENCES (2005)