Related references
Note: Only part of the references are listed.The Transcription Factor C/EBP delta Has Anti-Apoptotic and Anti-Inflammatory Roles in Pancreatic Beta Cells
Fabrice Moore et al.
PLOS ONE (2012)
The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines
Decio L. Eizirik et al.
PLOS GENETICS (2012)
PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Pancreatic β-Cell Apoptosis via Regulation of the BH3-Only Protein Bim
Izortze Santin et al.
DIABETES (2011)
INTERFERON-INDUCED GENE EXPRESSION IN CERVICAL MUCOSA DURING HUMAN PAPILLOMAVIRUS INFECTION
A. Pierangeli et al.
INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY (2011)
STAT1 Is a Master Regulator of Pancreatic β-Cell Apoptosis and Islet Inflammation
Fabrice Moore et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Cytokines Tumor Necrosis Factor-α and Interferon-γ Induce Pancreatic β-Cell Apoptosis through STAT1-mediated Bim Protein Activation
Jenny Barthson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Understanding type 1 diabetes through genetics: advances and prospects
Constantin Polychronakos et al.
NATURE REVIEWS GENETICS (2011)
Bcl-2 proteins in diabetes: mitochondrial pathways of β-cell death and dysfunction
Esteban N. Gurzov et al.
TRENDS IN CELL BIOLOGY (2011)
Exposure to the Viral By-Product dsRNA or Coxsackievirus B5 Triggers Pancreatic Beta Cell Apoptosis via a Bim/Mcl-1 Imbalance
Maikel L. Colli et al.
PLOS PATHOGENS (2011)
STAT2 Mediates Innate Immunity to Dengue Virus in the Absence of STAT1 via the Type I Interferon Receptor
Stuart T. Perry et al.
PLOS PATHOGENS (2011)
Identification of USP18 as an Important Regulator of the Susceptibility to IFN-α and Drug-Induced Apoptosis
Harish Potu et al.
CANCER RESEARCH (2010)
Islet inflammation and CXCL10 in recent-onset type 1 diabetes
B. O. Roep et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2010)
Cytokines Interleukin-1β and Tumor Necrosis Factor-α Regulate Different Transcriptional and Alternative Splicing Networks in Primary β-Cells
Fernanda Ortis et al.
DIABETES (2010)
MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic beta-cell responses to the viral by-product double-stranded RNA
Maikel L. Colli et al.
HUMAN MOLECULAR GENETICS (2010)
p53 Up-regulated Modulator of Apoptosis (PUMA) Activation Contributes to Pancreatic β-Cell Apoptosis Induced by Proinflammatory Cytokines and Endoplasmic Reticulum Stress
Esteban N. Gurzov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk
Matthias Heinig et al.
NATURE (2010)
Mitochondria and cell death: outer membrane permeabilization and beyond
Stephen W. G. Tait et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Signaling by IL-1β + IFN-γ and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic β-cell apoptosis
E. N. Gurzov et al.
CELL DEATH AND DIFFERENTIATION (2009)
PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Interferon-γ-Induced Pancreatic β-Cell Apoptosis
Fabrice Moore et al.
DIABETES (2009)
Enterovirus Infection, CXC Chemokine Ligand 10 (CXCL10), and CXCR3 Circuit A Mechanism of Accelerated β-Cell Failure in Fulminant Type 1 Diabetes
Shoichiro Tanaka et al.
DIABETES (2009)
Alpha Interferon Induces Long-Lasting Refractoriness of JAK-STAT Signaling in the Mouse Liver through Induction of USP18/UBP43
Magdalena Sarasin-Filipowicz et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
The role of inflammation in insulitis and β-cell loss in type 1 diabetes
Decio L. Eizirik et al.
NATURE REVIEWS ENDOCRINOLOGY (2009)
Epstein-Barr Virus Independent Dysregulation of UBP43 Expression Alters Interferon-Stimulated Gene Expression in Burkitt Lymphoma
Ingrid K. Ruf et al.
PLOS ONE (2009)
Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes
HyeonJoo Cheon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Prediction and Interaction in Complex Disease Genetics: Experience in Type 1 Diabetes
David G. Clayton
PLOS GENETICS (2009)
Induction of nuclear factor-κB and its downstream genes by TNF-α and IL-1β has a pro-apoptotic role in pancreatic beta cells
F. Ortis et al.
DIABETOLOGIA (2008)
Interferon-α initiates type 1 diabetes in nonobese diabetic mice
Qing Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Essential role for signal transducer and activator of transcription-1 in pancreatic β-cell death and autoimmune type 1 diabetes of nonobese diabetic mice
Sunshin Kim et al.
DIABETES (2007)
Deletion of STAT-1 pancreatic islets protects against streptozotocin-induced diabetes and early graft failure but not against late rejection
Hanne I. Callewaert et al.
DIABETES (2007)
Ubp43 regulates BCR-ABL leukemogenesis via the type 1 interferon receptor signaling
Ming Yan et al.
BLOOD (2007)
Microarray analysis reveals that Type I interferon strongly increases the expression of immune-response related genes in Ubp43 (Usp18) deficient macrophages
Weiguo Zou et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Coxsackie B4 virus infection of β cells and natural killer cell insulitis in recent-onset type 1 diabetic patients
Francesco Dotta et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity
Oxana A. Malakhova et al.
EMBO JOURNAL (2006)
Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA plus interferon-γ-induced apoptosis in primary pancreatic β-cells
J Rasschaert et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
ISG15: the immunological kin of ubiquitin
KJ Ritchie et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2004)
Neutralizing interferon alpha as a therapeutic approach to autoimmune diseases
TA Stewart
CYTOKINE & GROWTH FACTOR REVIEWS (2003)
Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets -: Evidence that β-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated
R Lupi et al.
DIABETES (2002)
UBP43 (USP18) specifically removes ISG15 from conjugated proteins
MP Malakhov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Increased level of interferon-α in blood of patients with insulin-dependent diabetes mellitus:: Relationship with coxsackievirus B infection
T Chehadeh et al.
JOURNAL OF INFECTIOUS DISEASES (2000)
Share Paper
