4.5 Article

Widely Conserved Signaling Pathways in the Establishment of Cell Polarity

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COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
DOI: 10.1101/cshperspect.a001370

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  1. National Institutes of Health [GM090702]
  2. Canadian Institutes of Health Research

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How are the asymmetric distributions of proteins, lipids, and RNAs established and maintained in various cell types? Studies from diverse organisms show that Par proteins, GTPases, kinases, and phosphoinositides participate in conserved signaling pathways to establish and maintain cell polarity.

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