Journal
MBIO
Volume 5, Issue 2, Pages -Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/mBio.00904-14
Keywords
-
Categories
Funding
- NIAID NIH HHS [P01 AI056320] Funding Source: Medline
Ask authors/readers for more resources
In most preclinical disease models, survival analyses are the gold standard for measuring the efficacy of medical interventions such as therapeutics or vaccines. In these analyses, treatment regimens that promote the survival and/or reduce the morbidity of experimental subjects (e.g., mice) are tested for efficacy. Although these analyses appear to be relatively straightforward, there are associated caveats regarding interpretation of the results that we wish to discuss in this editorial. Of particular concern is overinterpretation of the biological significance of survival data based on statistical significance rather than durability of protection.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available