Journal
MEDCHEMCOMM
Volume 4, Issue 2, Pages 367-370Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2md20275a
Keywords
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Funding
- National Natural Science Foundation of China [30973016]
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A series of quinoline derivatives were designed and synthesized as tyrosine kinase inhibitors. Exploration of the structure-activity relationships resulted in compounds that are potent in vitro. In addition, compound 10f was found to be a potent and selective Raf kinase inhibitor.
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