Journal
MEDCHEMCOMM
Volume 3, Issue 10, Pages 1305-1308Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2md20105d
Keywords
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Funding
- National Science Foundation [CHE-0952912]
- Welch Foundation [A-1423]
- USC Department of Radiology
- Department of Energy [DE-SC0002353]
- American Cancer Society [121991-MRSG-12-034-01-CCE]
- NNSF of Guangdong [U1032002]
- NNSF of China [81071206]
- National Cancer Institute [P30CA014089]
- Division Of Chemistry
- Direct For Mathematical & Physical Scien [0952912] Funding Source: National Science Foundation
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In this report, we show that [F-18]-zwitterionic aryltrifluoroborates with ortho-phosphonium groups are: (i) easily accessible via direct F-18-F-19 isotopic exchange reactions in aqueous solutions; and (ii) efficiently stabilized in vivo against fluoride ion dissociation.
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