4.1 Article

Development of novel ionic liquids based on ampicillin

Journal

MEDCHEMCOMM
Volume 3, Issue 4, Pages 494-497

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2md00269h

Keywords

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Funding

  1. Fundacao para a Ciencia e Tecnologia [PEst-C/EQB/LA0006/2011, PTDC/EQU-EPR/104554/2008, SFRH/BPD/65981/2009]
  2. Fundação para a Ciência e a Tecnologia [SFRH/BPD/65981/2009] Funding Source: FCT

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Novel ionic liquids containing ampicillin as an active pharmaceutical ingredient anion were prepared with good yields by using a new, efficient synthetic procedure based on the neutralization of a moderately basic ammonia solution of ampicillin with different organic cation hydroxides. The relevant physical and thermal properties of these novel ionic liquids based on ampicillin were also evaluated.

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