Related references
Note: Only part of the references are listed.The Clinical Relevance of Plasma Protein Binding Changes
Jason A. Roberts et al.
CLINICAL PHARMACOKINETICS (2013)
Effect of volume ratio of ultrafiltrate to sample solution on the analysis of free drug and measurement of free carbamazepine in clinical drug monitoring
Wei-chong Dong et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2013)
High performance affinity chromatography (HPAC) as a high-throughput screening tool in drug discovery to study drug-plasma protein interactions
Karine Vuignier et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2013)
A mass balance approach for calculation of recovery and binding enables the use of ultrafiltration as a rapid method for measurement of plasma protein binding for even highly lipophilic compounds
Changguang Wang et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2013)
Characterization of Drug Interactions with Serum Proteins by Using High-Performance Affinity Chromatography
David S. Hage et al.
CURRENT DRUG METABOLISM (2012)
Compilation of 222 drugs' plasma protein binding data and guidance for study designs
Fengling Zhang et al.
DRUG DISCOVERY TODAY (2012)
Development of a Flow-Based Ultrafast Immunoextraction and Reverse Displacement Immunoassay: Analysis of Free Drug Fractions
John E. Schiel et al.
ANALYTICAL CHEMISTRY (2011)
Do We Need to Optimize Plasma Protein and Tissue Binding in Drug Discovery?
Xingrong Liu et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2011)
Control and Measurement of Plasma pH in Equilibrium Dialysis: Influence on Drug Plasma Protein Binding
Ruth E. Curran et al.
DRUG METABOLISM AND DISPOSITION (2011)
Correction for Nonspecific Binding to Various Components of Ultrafiltration Apparatus and Impact on Estimating In Vivo Rat Clearance for a Congeneric Series of 5-Ethyl, 5-n-Alkyl Barbituric Acids
Peter Ballard et al.
DRUG METABOLISM AND DISPOSITION (2011)
Determination of unbound vismodegib (GDC-0449) concentration in human plasma using rapid equilibrium dialysis followed by solid phase extraction and high-performance liquid chromatography coupled to mass spectrometry
Yuzhong Deng et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2011)
Determination of unbound ticagrelor and its active metabolite (AR-C124910XX) in human plasma by equilibrium dialysis and LC-MS/MS
Henrik Sillen et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2011)
A kinetic method for the determination of plasma protein binding of compounds unstable in plasma: Specific application to enalapril
Mark C. Wenlock et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2011)
Validation of 96-well Equilibrium Dialysis with Non-radiolabeled Drug for Definitive Measurement of Protein Binding and Application to Clinical Development of Highly-Bound Drugs
Maciej J. Zamek-Gliszczynski et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2011)
Monitoring free drug concentrations: challenges
Florin Marcel Musteata
BIOANALYSIS (2011)
Drug-protein binding: a critical review of analytical tools
Karine Vuignier et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2010)
Improving the ex vivo stability of drug ester compounds in rat and dog serum: Inhibition of the specific esterases and implications on their identity
Matthias Koitka et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2010)
Significance of Protein Binding in Pharmacokinetics and Pharmacodynamics
Stephan Schmidt et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2010)
The effect of plasma protein binding on in vivo efficacy: misconceptions in drug discovery
Dennis A. Smith et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Ion suppression and enhancement effects of co-eluting analytes in multi-analyte approaches: systematic investigation using ultra-high-performance liquid chromatography/mass spectrometry with atmosphericpressure chemical ionization or electrospray ionization
Daniela Remane et al.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2010)
Utility of the carboxylesterase inhibitor bis-para-nitrophenylphosphate (BNPP) in the plasma unbound fraction determination for a hydrolytically unstable amide derivative and agonist of the TGR5 receptor
H. Eng et al.
XENOBIOTICA (2010)
Effective screening approach to select esterase inhibitors used for stabilizing ester-containing prodrugs analyzed by LC-MS/MS
Eliza N. Fung et al.
BIOANALYSIS (2010)
Consideration of the Linear Concentration Increase of the Unbound Drug Fraction in Plasma
Leonid M. Berezhkovskiy
JOURNAL OF PHARMACEUTICAL SCIENCES (2009)
Influence of Plasma Protein Binding on Pharmacodynamics: Estimation of In Vivo Receptor Affinities of β Blockers Using a New Mechanism-Based PK-PD Modelling Approach
T. J. Van Steeg et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2009)
Characterization of drug-protein interactions in blood using high-performance affinity chromatography
David S. Hage et al.
JOURNAL OF SEPARATION SCIENCE (2009)
Plasma/Serum Protein Binding Determinations
Michael J. Banker et al.
CURRENT DRUG METABOLISM (2008)
Some features of the kinetics and equilibrium of drug binding to plasma proteins
Leonid M. Berezhkovskiy
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2008)
Impact of pH on plasma protein binding in equilibrium dialysis
Christopher J. Kochansky et al.
MOLECULAR PHARMACEUTICS (2008)
Usefulness of monitoring free (unbound) concentrations of therapeutic drugs in patient management
Amitava Dasgupta
CLINICA CHIMICA ACTA (2007)
Analysis of free drug fractions using near-infrared fluorescent labels and an ultrafast immunoextraction/displacement assay
Corey M. Ohnmacht et al.
ANALYTICAL CHEMISTRY (2006)
Investigation of high-throughput ultrafiltration for the determination of an unbound compound in human plasma using liquid chromatography and tandem mass spectrometry with electrospray ionization
Jin Zhang et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2006)
Characterization of drug-binding levels to serum albumin using a wavelength modulation surface plasmon resonance sensor
Xia Liu et al.
SENSORS AND ACTUATORS B-CHEMICAL (2006)
Stereoselective pharmacokinetics of cetirizine in the guinea pig: Role of protein binding
Anubha Gupta et al.
BIOPHARMACEUTICS & DRUG DISPOSITION (2006)
Modification of the ultrafiltration technique to overcome solubility and non-specific binding challenges associated with the measurement of plasma protein binding of corticosteroids
S Taylor et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2006)
High-throughput screening of protein binding by equilibrium dialysis combined with liquid chromatography and mass spectrometry
H Wan et al.
JOURNAL OF CHROMATOGRAPHY A (2006)
The role of unbound drug in pharmacokinetics/pharmacodynamics and in therapy
R Calvo et al.
CURRENT PHARMACEUTICAL DESIGN (2006)
Effect of ultrafiltrate volume on determination of free phenytoin concentration
Gwen A. McMillin et al.
THERAPEUTIC DRUG MONITORING (2005)
Stabilizing drug molecules in biological samples
Jiwen Chen et al.
THERAPEUTIC DRUG MONITORING (2005)
Studies of drug binding to plasma proteins using a variant of equilibrium dialysis
MAL Eriksson et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2005)
The pH dependency of the binding of drugs to plasma proteins in man
PH Hinderling et al.
THERAPEUTIC DRUG MONITORING (2005)
High-throughout determination of the free fraction of drugs strongly bound to plasma proteins
J Schuhmacher et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2004)
Measurement of free concentrations using negligible depletion-solid phase microextraction (nd-SPME)
MB Heringa et al.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2003)
Shift in pH of biological fluids during storage and processing: effect on bioanalysis
A Fura et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2003)
Modulation of nonspecific binding in ultrafiltration protein binding studies
KJ Lee et al.
PHARMACEUTICAL RESEARCH (2003)
Influence of the ORMI phenotypes on serum unbound concentration and protein binding of quinidine
JH Li et al.
CLINICA CHIMICA ACTA (2002)
Chiral separation by chromatographic and electromigration techniques.: A review
G Gübitz et al.
BIOPHARMACEUTICS & DRUG DISPOSITION (2001)
Validation of methods to study the distribution and protein binding of tacrolimus in human blood
H Zahir et al.
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2001)
Effect of temperature on serum protein binding characteristics of phenytoin in monotherapy paediatric patients with epilepsy
H Kodama et al.
JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS (2001)
Simultaneous determination of total and free drug plasma concentrations combined with batch-wise pH-adjustment for the free concentration determinations
LB Nilsson et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2001)
The role of albumin in critical illness
JP Nicholson et al.
BRITISH JOURNAL OF ANAESTHESIA (2000)
Evaluation of solid-phase microextraction for the study of protein binding in human plasma samples
M Abdel-Rehim et al.
JOURNAL OF CHROMATOGRAPHIC SCIENCE (2000)