4.3 Editorial Material

Important considerations for quantitation of small-molecule biomarkers using LC-MS

Journal

BIOANALYSIS
Volume 4, Issue 20, Pages 2431-2434

Publisher

FUTURE SCI LTD
DOI: 10.4155/BIO.12.247

Keywords

authentic analyte; authentic matrix; endogenous analyte; exogenous analyte; surrogate analyte; surrogate matrix

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In our opinion, dealing with endogenous levels of the analyte, confirming specificity of the assay, maintaining analyte integrity ex vivo and designing the proper study protocol, comprise the most important aspects of successful biomarker assay development.

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