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JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2003)
Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS
BK Matuszewski et al.
ANALYTICAL CHEMISTRY (2003)
Modulation of nonspecific binding in ultrafiltration protein binding studies
KJ Lee et al.
PHARMACEUTICAL RESEARCH (2003)
Ion suppression in mass spectrometry
TM Annesley
CLINICAL CHEMISTRY (2003)
Generic solid phase extraction-liquid chromatography-tandem mass spectrometry method for fast determination of drugs in biological fluids
A Schellen et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2003)
Simultaneous quantification of seven active metabolites of roxifiban in human plasma by LC/MS/MS in the presence of an interfering displacer at millimolar concentrations
G Shi et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2003)
Dissociation of individual isotopic peaks:: Predicting isotopic distributions of product ions in MSn
AL Rockwood et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2003)
Optimization of protein precipitation based upon effectiveness of protein removal and ionization effect in liquid chromatography-tandem mass spectrometry
C Polson et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2003)
Demonstration of direct bioanalysis of drugs in plasma using nanoelectrospray infusion from a silicon chip coupled with tandem mass spectrometry
JM Dethy et al.
ANALYTICAL CHEMISTRY (2003)
Synthesis and evaluation-of PEG414, a novel formulating agent that avoids analytical problems associated with polydisperse vehicles such as PEG400
D Temesi et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2003)
Post-column infusion study of the 'dosing vehicle effect' in the liquid chromatography/tandem mass spectrometric analysis of discovery pharmacokinetic samples
WZ Shou et al.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2003)
Investigation of matrix effects in bioanalytical high-performance liquid chromatography/tandem mass spectrometric assays: application to drug discovery
H Mei et al.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2003)
Ionization enhancement in atmospheric pressure chemical ionization and suppression in electrospray ionization between target drugs and stable-isotope-labeled internal standards in quantitative liquid chromatography/tandem mass spectrometry
HR Liang et al.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2003)
Liquid chromatography/tandem mass spectrometry methods for quantitation of mevalonic acid in human plasma and urine: method validation, demonstration of using a surrogate analyte, and demonstration of unacceptable matrix effect in spite of use of a stable isotope analog internal standard
M Jemal et al.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2003)
Quantitative characterization of differential ion suppression on liquid chromatography/atmospheric pressure ionization mass spectrometric bioanalytical methods
MJ Avery
RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2003)
Internal standard signal suppression by co-eluting analyte in isotope dilution LC-ESI-MS
LE Sojo et al.
ANALYST (2003)
Effect of signal interference from dosing excipients on pharmacokinetic screening of drug candidates by liquid chromatography/mass spectrometry
XCS Tong et al.
ANALYTICAL CHEMISTRY (2002)
In vitro stability and in vivo pharmacokinetic studies of a model opioid peptide, H-Tyr-D-Ala-Gly-Phe-D-Leu-OH (DADLE), and its cyclic prodrugs
JZ Yang et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
Ion suppression effects in liquid chromatography-electrospray-ionisation transport-region collision induced dissociation mass spectrometry with different serum extraction methods for systematic toxicological analysis with mass spectra libraries
C Müller et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2002)
High-performance liquid chromatographic-tandem mass spectrometric evaluation and determination of stable isotope labeled analogs of rofecoxib in human plasma samples from oral bioavailability studies
CM Chavez-Eng et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2002)
LC-MS-MS experiences with internal standards
J Wieling
CHROMATOGRAPHIA (2002)
Reduction in matrix-related signal suppression effects in electrospray ionization mass spectrometry using on-line two-dimensional liquid chromatography
R Pascoe et al.
ANALYTICAL CHEMISTRY (2001)
Reduction of signal suppression effects in ESI-MS using a nanosplitting device
ET Gangl et al.
ANALYTICAL CHEMISTRY (2001)
Determination of scutellarin in Erigeron breviscapus extract by liquid chromatography-tandem mass spectrometry
J Qu et al.
JOURNAL OF CHROMATOGRAPHY A (2001)
Improvement in precision of the liquid chromatographic-electrospray ionization tandem mass spectrometric analysis of 3′-C-ethynylcytidine in rat plasma
R Kitamura et al.
JOURNAL OF CHROMATOGRAPHY B (2001)
Atmospheric pressure chemical ionization mass spectrometry for analysis of lipids
WC Byrdwell
LIPIDS (2001)
Effect of anticoagulants and storage temperatures on stability of plasma and serum hormones
MJ Evans et al.
CLINICAL BIOCHEMISTRY (2001)
Determination of pibutidine metabolites in human plasma by LC-MS/MS
K Kato et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2000)
Protonation in electrospray mass spectrometry: Wrong-way-round or right-way-round?
SL Zhou et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2000)
Mechanistic investigation of ionization suppression in electrospray ionization
R King et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2000)