4.3 Review

miRNAs as biomarkers in colorectal cancer diagnosis and prognosis

Journal

BIOANALYSIS
Volume 2, Issue 5, Pages 901-906

Publisher

FUTURE SCI LTD
DOI: 10.4155/BIO.10.45

Keywords

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Funding

  1. [MH075020]
  2. NATIONAL CANCER INSTITUTE [R21CA114043] Funding Source: NIH RePORTER
  3. NATIONAL INSTITUTE OF MENTAL HEALTH [R01MH075020] Funding Source: NIH RePORTER

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Since the discovery of noncoding small miRNAs and their function in controlling mRNA translational rate, the small non-coding miRNA world has become a research wonderland for cancer and other human diseases. Due to the critical regulatory function, miRNA can act as an oncogene or a tumor-suppressor gene. This review will cover some of the recent discoveries of the potential of miRNAs as cancer biomarkers in colorectal cancer, future challenges and solutions.

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