Related references
Note: Only part of the references are listed.Beyond pathology: APP, brain development and Alzheimer's disease
Alessia Soldano et al.
CURRENT OPINION IN NEUROBIOLOGY (2014)
Amyloid Precursor Protein Dimerization and Synaptogenic Function Depend on Copper Binding to the Growth Factor-Like Domain
Frederik Baumkoetter et al.
JOURNAL OF NEUROSCIENCE (2014)
Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins
Benjamin G. Wilhelm et al.
SCIENCE (2014)
Comparative analysis of single and combined APP/APLP knockouts reveals reduced spine density in APP-KO mice that is prevented by APPsa expression
Sascha W. Weyer et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2014)
Postnatal Disruption of the Disintegrin/Metalloproteinase ADAM10 in Brain Causes Epileptic Seizures, Learning Deficits, Altered Spine Morphology, and Defective Synaptic Functions
Johannes Prox et al.
JOURNAL OF NEUROSCIENCE (2013)
The Specific α-Neurexin Interactor Calsyntenin-3 Promotes Excitatory and Inhibitory Synapse Development
Katherine L. Pettem et al.
NEURON (2013)
Amyloid precursor protein (APP) regulates synaptic structure and function
Sheue-Houy Tyan et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2012)
Activity-Dependent Proteolytic Cleavage of Neuroligin-1
Kunimichi Suzuki et al.
NEURON (2012)
Synaptic Cell Adhesion
Markus Missler et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
Physiological Functions of APP Family Proteins
Ulrike C. Mueller et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
Structural aspects and physiological consequences of APP/APLP trans-dimerization
Frederik Baumkoetter et al.
EXPERIMENTAL BRAIN RESEARCH (2012)
Analysis of amyloid precursor protein function in Drosophila melanogaster
Burkhard Poeck et al.
EXPERIMENTAL BRAIN RESEARCH (2012)
Synaptic organizing complexes
Tabrez J. Siddiqui et al.
CURRENT OPINION IN NEUROBIOLOGY (2011)
APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP
Sascha W. Weyer et al.
EMBO JOURNAL (2011)
ADAM10 is the physiologically relevant, constitutive α-secretase of the amyloid precursor protein in primary neurons
Peer-Hendrik Kuhn et al.
EMBO JOURNAL (2010)
BETA AMYLOID-INDEPENDENT ROLE OF AMYLOID PRECURSOR PROTEIN IN GENERATION AND MAINTENANCE OF DENDRITIC SPINES
K. J. Lee et al.
NEUROSCIENCE (2010)
Structure and biochemical analysis of the heparin-induced E1 dimer of the amyloid precursor protein
Sven O. Dahms et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors
Kristin T. Jacobsen et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2009)
Induced Dimerization of the Amyloid Precursor Protein Leads to Decreased Amyloid-β Protein Production
Simone Eggert et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Subcellular localization and dimerization of APLP1 are strikingly different from APP and APLP2
Daniela Kaden et al.
JOURNAL OF CELL SCIENCE (2009)
Interaction of Reelin with Amyloid Precursor Protein Promotes Neurite Outgrowth
Hyang-Sook Hoe et al.
JOURNAL OF NEUROSCIENCE (2009)
Presynaptic and Postsynaptic Interaction of the Amyloid Precursor Protein Promotes Peripheral and Central Synaptogenesis
Zilai Wang et al.
JOURNAL OF NEUROSCIENCE (2009)
Neurotoxic effects induced by the Drosophila amyloid-β peptide suggest a conserved toxic function
Katia Carmine-Simmen et al.
NEUROBIOLOGY OF DISEASE (2009)
Amyloid-β-anti-amyloid-β complex structure reveals an extended conformation in the immunodominant B-Cell epitope
Luke A. Miles et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Neuroligins and neurexins link synaptic function to cognitive disease
Thomas C. Sudhof
NATURE (2008)
Endogenous secreted amyloid precursor protein-α regulates hippocampal NMDA receptor function, long-term potentiation and spatial memory
Chanel J. Taylor et al.
NEUROBIOLOGY OF DISEASE (2008)
A critical function for β-amyloid precursor protein in neuronal migration revealed by In Utero RNA interference
Tracy L. Young-Pearse et al.
JOURNAL OF NEUROSCIENCE (2007)
SynCAMs organize synapses through heterophilic adhesion
Adam I. Fogel et al.
JOURNAL OF NEUROSCIENCE (2007)
β-amyloid precursor protein can be transported independent of any sorting signal to the axonal and dendritic compartment
Simone Back et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2007)
The secreted β-amyloid precursor protein ectodomain APPsα is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice
Sabine Ring et al.
JOURNAL OF NEUROSCIENCE (2007)
The APP family of proteins: similarities and differences
D. M. Walsh et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2007)
Mixed-culture assays for analyzing neuronal synapse formation
Thomas Biederer et al.
NATURE PROTOCOLS (2007)
Cell adhesion molecules: signalling functions at the synapse
Matthew B. Dalva et al.
NATURE REVIEWS NEUROSCIENCE (2007)
Equimolar production of amyloid β-protein and amyloid precursor protein intracellular domain from β-carboxyl-terminal fragment by β-secretase
Nobuto Kakuda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The amyloid-β precursor protein:: integrating structure with biological function
C Reinhard et al.
EMBO JOURNAL (2005)
Homo- and heterodimerization of APP family members promotes intercellular adhesion
P Soba et al.
EMBO JOURNAL (2005)
ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and, β-catenin translocation
T Maretzky et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Characterization of Drosophila aspartic proteases that induce the secretion of a Golgi-resident transferase, heparan sulfate 6-O-sulfotransferase
N Kotani et al.
JOURNAL OF BIOCHEMISTRY (2005)
Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-like protein 2
P Wang et al.
JOURNAL OF NEUROSCIENCE (2005)
Activation of EGF receptor kinase by L1-mediated homophilic cell interactions
R Islam et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins
ER Graf et al.
CELL (2004)
Coordinated metabolism of alcadein and amyloid β-protein precursor regulates FE65-dependent gene transactivation
Y Araki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members
J Herms et al.
EMBO JOURNAL (2004)
The disintegrin-like metalloproteinase ADAM 10 is involved in coinstitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion
C Hundhausen et al.
BLOOD (2003)
The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and γ-secretase
E Six et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
A novel ε-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with notch processing
A Weidemann et al.
BIOCHEMISTRY (2002)
Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons
P Scheiffele et al.
CELL (2000)
A new aspartyl protease on 21q22.3, BACE2, is highly similar to Alzheimer's amyloid precursor protein beta-secretase
A Solans et al.
CYTOGENETICS AND CELL GENETICS (2000)