Journal
JOURNAL OF MATERIALS CHEMISTRY C
Volume 3, Issue 15, Pages 3517-3521Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5tc00369e
Keywords
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Funding
- National Natural Science Foundation of China [21272093, 51473061]
- Fundamental Research Funds for the Central Universities [JCKY-QKJC05]
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We present a facile one-step procedure for the solvothermal synthesis of highly water-dispersible magnetic Fe3O4 nanoparticles mediated by cucurbit[n]urils (CB[n]s). A layer of CB[n] s was coated on the MNP surface via the portal carbonyl groups to avoid MNP agglomeration, and served as a stabilizer to impart the nanoparticles with exceptional dispersibility and stability. Significantly, the nanoparticle sizes can be controlled and fine-tuned by varying the molar ratios of CB[n]s and FeCl3 in solution. The biocompatibility of the materials was investigated by MTT assay using normal human embryonic kidney 293T cells. The synergetic effects of combining supramolecular chemistry with magnetic nanoparticles are promising for clinical diagnosis and transportation of drugs, proteins, viruses, bacteria, etc., which offer important advantageous features for their real applications.
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