Synthesis of new derivatives of pyrimido[5,4-e][1,2,4]triazolo[3,4-b][1,3,4]thiadiazine and their enzyme inhibitory activity assessment on soybean 15-lipoxygenase

The synthesis of new derivatives of pyrimido[5,4-e][1,2,4]triazolo[3,4-b][1,3,4]thiadiazine is described. These derivatives have a wide range of medicinal applications. Their inhibitory activity against the enzyme 15-lipoxygenase was also investigated.