Journal
JOURNAL OF CHEMICAL RESEARCH
Volume -, Issue 8, Pages 463-467Publisher
SAGE PUBLICATIONS LTD
DOI: 10.3184/174751912X13395258340271
Keywords
ionic liquid; [Hpyro][HSO4]; heterocycle; piperidine; homogeneous catalyst
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Funding
- Research Council of the University of Sistan and Baluchestan
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1-Methyl-2-oxopyrrolidinium hydrogen sulfate ([Hpyro][HSO4]) is used as an ionic liquid catalyst for the one-pot three-component synthesis of highly substituted piperidines from aromatic aldehydes, anilines and beta-ketoesters in refluxing ethanol. This homogeneous catalyst procedure has the advantages of easy work-up, no need for column chromatography, simple and readily available precursors, and good to high yields.
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