Journal
JOURNAL OF CHEMICAL RESEARCH
Volume -, Issue 2, Pages 84-86Publisher
SCIENCE REVIEWS 2000 LTD
DOI: 10.3184/030823409X401844
Keywords
imidazo[1,2-a]pyridines; 2,4-disubstituted thiazoles; grinding; solvent-free synthesis; catalyst-free synthesis
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Funding
- National Key Technology RD Program [2007BAI34B00]
- Natural Science Foundation of Zhengjiang Province [Y4080107]
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An efficient synthesis of imidazo[1,2-a]pyridines and 2,4-disubstituted thiazoles in excellent yield under catalyst and solvent-free conditions at room temperature on grinding has been developed. The important features of this method are that it is reasonably fast, very clean, high yielding, simple workup and environmentally benign.
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