Journal
JOURNAL OF CHEMICAL RESEARCH
Volume -, Issue 10, Pages 564-565Publisher
SCIENCE REVIEWS 2000 LTD
DOI: 10.3184/030823408X356314
Keywords
2-aminofuronitrile; furo[2,3-d]pyrimidine; heterocyclisation; phenacyl bromides
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Solvent-free reaction of substituted alpha-haloketones with malononitrile in the presence of diethylamine provides an efficient one-pot synthesis of 2-amino-5-aryl (alkyl)-3-furonitriles in high yield.
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