Journal
CHEMICAL SCIENCE
Volume 4, Issue 9, Pages 3421-3426Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3sc51424b
Keywords
-
Categories
Funding
- NNSFC [21202143]
- Fundamental Research Funds for the Central Universities [2012QNA7020, 2013QNA7014]
- Zhejiang University
Ask authors/readers for more resources
An unprecedented Rh(III)-catalyzed C-Hactivation/cycloaddition of benzamides and methylenecyclopropanes for the selective synthesis of spiro dihydroisoquinolinones and furan-fused azepinones is reported. The process features simple starting materials, mild conditions, and high efficiency and is external oxidant free. The products could be easily converted to other biologically interesting heterocycles. Control experiments and kinetic isotope effect studies were conducted and a plausible mechanism is proposed.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available